#World journal how to#

The objectives of this study were therefore to prepare and characterize transferrin-conjugated lipid-polymer hybrid nanoparticles (LPHN) entrapping α-mangostin, as well as to evaluate their therapeutic efficacy in vitro. We hypothesized that this drawback could be overcome by loading the drug within a delivery system conjugated to transferrin (Tf), whose receptors are overexpressed on many cancer cells and would enhance the specific delivery of α-mangostin to cancer cells, thereby enhancing its therapeutic efficacy. Furthermore, α-mangostin failed to specifically reach tumors at a therapeutic concentration due and rapid elimination in vivo. However, the therapeutic potential of α-mangostin has been limited so far due to its poor aqueous solubility and low oral bioavailability, which limited its biopharmaceutical applications. | Srisopa RuangnooĪlpha-mangostin, a natural xanthone mainly extracted from the pericarp of Garcinia mangostana, has been shown to have promising anticancer properties in many types of cancer. Intouch Sakpakdeejaroen | Patcharaporn Muanrit |.

#World journal how to#

Future studies should concentrate on how to boost sesame output in farmers’ fields while following appropriate sesame production technology and agronomic principles. Farmers, policymakers, researchers, and other stakeholders must thus intervene to enhance sesame production. In a nutshell, an increased area under cultivation combined with best agronomic practices could boost sesame production. This will contribute to Ethiopia’s ongoing discussion about how to better inform private and public sector policies and investments to increase sesame production, transform agriculture, improve nutrition and food systems, and be able to ease supply- and demand-side restrictions. If farmers, dealers, and the government do not address these issues strategically, the country may soon lose its competitiveness in the global sesame seed market. Ethiopia’s sesame seed development potential is being severely hampered by these restrictions.

Other demand-side constraints include worldwide price volatility, a highly concentrated export market, and intense global competition.

On the demand side, traders and market distortion, as well as an artificially higher home price and the ease with which unskilled labor can enter the market, are all factors. Reduced sesame productivity, pests and diseases, and limited access to modern technologies are all severe supply-side constraints. Millions of growers and other market participants are employed throughout the oilseed value chain. Various exclusion and inclusion criteria were used to filter the most notable findings. We established a comprehensive scientific understanding of the crop using a systematic review of the current literature and deductive logical reasoning that can be used to inform future research and policies. It is a highly adaptable crop that may be used for anything from subsistence to commercial output. This paper begins with an examination of one of the most prominent oil crops in the country. Even though Ethiopia is one of the world’s largest producers and exporters of sesame seeds, the country is facing increasing supply and demand restrictions. Ethiopia’s three main oilseed crops (sesame, soybean, and Niger seed) account for about 20% of the country’s total agricultural export profits, second only to coffee. Thus, for the profitable iron extraction, other factors such as coverage of ores, extraction costs, and market value should be considered.Įthiopia’s oilseed industry makes a major contribution to foreign exchange revenues. Based on the chemical analysis, the Fe content in the collected hematite sample is in intermediate range. The findings of different parameters in percentage areas follows: loss on ignition (1.76 ± 0.17), silica (47.06 ± 4.01), and iron (36.75 ± 2.50) by titrimetric analysis. Chemical analysis was carried out by gravimetric, titrimetric, UV-Vis spectrophotometric and atomic absorption spectroscopic methods. Sampling of the hematite ore was performed by channel sampling method. In this work, quantitative chemical analysis of iron was carried out from the collected seventy-two hematite samples from Pokhari, Nawalparasi. Quantitative and qualitative estimation of iron in its ores is a crucial factor before its extraction. Iron is the principal raw material for steel industries and Hematite is a principal ore of iron. Ram Bahadur Gharti | Hari Bhakta Oli | Deval Prasad Bhattarai